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Current Affairs Of the Day - 18th Feb, 2023 :- Welcome to the Class24 Current Affairs website which provides you with the best compilation of the Daily Current Affairs 2022 taking place across the globe: National issues, International news, Sports covers, Science and Tech, Banking, Economy, Agreement, Appointments, Ranks and Report and General Studies.
Pan-Transcriptome
Recently, researchers at the University of California, Santa Cruz, have proposed a “Pan-transcriptome” which combines a transcriptome and a pan-genome.
Mapping transcriptome (complete set of RNA molecules) allows researchers to better understand an individual’s gene expression.
What is a ‘Pan-transcriptome’?
Pan-transcriptome is a reference that contains genetic material from a cohort of diverse individuals, rather than just a single linear strand.
A "pan-transcriptome" is a combination of a transcriptome and a pan-genome.
Transcriptome
A transcriptome is the complete set of RNA molecules in a cell or tissue including mRNA, rRNA, tRNA, and other non-coding RNA, that are produced by the genetic material of an organism.
It is the complement of the genome, which is the entire set of genetic material in an organism.
Pan-genome
A pan-genome is a reference that contains genetic material from a diverse group of individuals, rather than just a single linear strand.
Using a pangenome allows researchers to compare an individual’s genome to that of a genetically diverse cohort of reference sequences all at once, sourced from individuals representing a diversity of biogeographic ancestry.
What is the Use of Pan-transcriptome?
Discovery of New Gene
Regulating Gene Expression
Characterizing Genetic Diversity
What is RNA Mapping?
RNA mapping is a technique used to identify and map the location of RNA molecules within a cell or tissue.
It is typically used to study the expression and localization of different types of RNA, including messenger RNA (mRNA), ribosomal RNA (rRNA), and transfer RNA (tRNA).
पैन-ट्रांसक्रिप्टोम
• हाल ही में, कैलिफोर्निया विश्वविद्यालय, सांता क्रूज़ के शोधकर्ताओं ने एक "पैन-ट्रांसक्रिप्टोम" का प्रस्ताव दिया है जो एक ट्रांसक्रिप्टोम और एक पैन-जीनोम को जोड़ता है।
• मैपिंग ट्रांसक्रिप्टोम (आरएनए अणुओं का पूरा सेट) शोधकर्ताओं को किसी व्यक्ति की जीन अभिव्यक्ति को बेहतर ढंग से समझने की अनुमति देता है।
'पैन-ट्रांसक्रिप्टोम' क्या है?
• पैन-ट्रांसक्रिप्टोम एक ऐसा संदर्भ है जिसमें केवल एक रैखिक स्ट्रैंड के बजाय विविध व्यक्तियों के समूह से आनुवंशिक सामग्री शामिल होती है।
• एक "पैन-ट्रांसक्रिप्टोम" एक ट्रांसक्रिप्टोम और एक पैन-जीनोम का संयोजन है।
ट्रांसक्रिप्टोम
• एक प्रतिलेख एक कोशिका या ऊतक में आरएनए अणुओं का पूरा सेट है जिसमें एमआरएनए, आरआरएनए, टीआरएनए और अन्य गैर-कोडिंग आरएनए शामिल हैं, जो एक जीव की आनुवंशिक सामग्री द्वारा निर्मित होते हैं।
• यह जीनोम का पूरक है, जो एक जीव में अनुवांशिक सामग्री का पूरा सेट है।
अखिल जीनोम
• एक पैन-जीनोम एक संदर्भ है जिसमें व्यक्तियों के एक विविध समूह से आनुवंशिक सामग्री होती है, न कि केवल एक रैखिक किनारा।
• एक पैन्जेनोम का उपयोग करने से शोधकर्ताओं को एक व्यक्ति के जीनोम की तुलना संदर्भ अनुक्रमों के एक आनुवंशिक रूप से विविध समूह से करने की अनुमति मिलती है, जो जैव-भौगोलिक वंश की विविधता का प्रतिनिधित्व करने वाले व्यक्तियों से प्राप्त होता है।
पैन-ट्रांसक्रिप्टोम का उपयोग क्या है?
• नए जीन की खोज
• जीन अभिव्यक्ति का विनियमन
• विशेषता आनुवंशिक विविधता
आरएनए मैपिंग क्या है?
• आरएनए मैपिंग एक ऐसी तकनीक है जिसका उपयोग सेल या ऊतक के भीतर आरएनए अणुओं के स्थान की पहचान करने और मैप करने के लिए किया जाता है।
• यह आम तौर पर मैसेंजर आरएनए (एमआरएनए), राइबोसोमल आरएनए (आरआरएनए), और ट्रांसफर आरएनए (टीआरएनए) सहित विभिन्न प्रकार के आरएनए की अभिव्यक्ति और स्थानीयकरण का अध्ययन करने के लिए उपयोग किया जाता है।
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